A patient develops fever and diaphoresis after receiving benzathine penicillin G. What is the best treatment option?

Prepare for the Rosh Internal Medicine Boost End of Rotation (EOR) Exam with flashcards and multiple-choice questions. Each question offers hints and explanations to help you excel. Get exam-ready now!

In this scenario, the patient has developed fever and diaphoresis following the administration of benzathine penicillin G, which can indicate a reaction to the medication, such as a hypersensitivity response or an infusion-related reaction. The best treatment option among the choices presented is ibuprofen.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can help manage fever and discomfort associated with inflammatory responses. It works by inhibiting the production of prostaglandins, which play a role in the inflammatory process. By reducing fever and managing the associated symptoms like diaphoresis, ibuprofen provides symptomatic relief for the patient.

In contrast, other options such as ceftriaxone are antibiotics that would not be appropriate in this context since the patient is already receiving treatment with benzathine penicillin G, and there's no indication for a secondary antibiotic at this moment. Diphenhydramine, an antihistamine, might be useful if an allergic reaction is suspected, but it would not specifically address the symptoms of fever and diaphoresis. Dobutamine, a medication primarily used for heart failure and low cardiac output, is unrelated to the management of fever or hypersensitivity reactions and would not be appropriate in this situation. Using ib

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