What is the typical clinical manifestation of hyperthyroidism?

The typical clinical manifestation of hyperthyroidism includes weight loss and heat intolerance. In hyperthyroidism, there is an overproduction of thyroid hormones, which accelerates metabolism. This results in an increase in energy expenditure, leading to unintended weight loss despite normal or increased appetite.

Heat intolerance is another common symptom, as the increased metabolic activity can cause excessive sweating and discomfort in warm environments. Patients may feel excessively warm and have a low tolerance for heat due to the heightened metabolic rate.

Other symptoms often seen alongside weight loss and heat intolerance include palpitations, nervousness, increased sweating, and changes in bowel habits, such as diarrhea. These combined symptoms reflect the body's heightened state of activity due to excess thyroid hormone levels.