Which type of diabetes is most likely to result in ketoacidosis?

Type 1 diabetes mellitus is the type of diabetes most likely to result in ketoacidosis due to its pathophysiology. In Type 1 diabetes, the body is unable to produce insulin because the insulin-producing beta cells in the pancreas are destroyed by an autoimmune process. Insulin is essential for allowing glucose to enter cells for energy. Without adequate insulin, the body cannot use glucose effectively, leading to an accumulation of glucose in the bloodstream.

In response to the lack of insulin, the body starts to break down fat as an alternative source of energy. This process results in the formation of ketones, which can accumulate to dangerous levels, leading to diabetic ketoacidosis (DKA). DKA is characterized by hyperglycemia, ketonuria, acidosis, and electrolyte imbalances. This condition is more common in individuals with Type 1 diabetes, especially when insulin is not administered or when there are triggering factors such as infection, stress, or missed doses of insulin.

In contrast, Type 2 diabetes generally has a sufficient level of insulin production, at least initially, preventing the compounded breakdown of fats and subsequent development of ketoacidosis. Gestational diabetes primarily concerns glucose management during pregnancy and does not lead to ketoacidosis in the same